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Clinical Problem Solving: Pathology |

Pathology Quiz Case 1: Diagnosis

Arch Otolaryngol Head Neck Surg. 2012;138(3):314-315. doi:10.1001/archoto.2011.1231b.
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Eeles RA, Fisher C, A’Hern RP,  et al. Head and neck sarcomas: prognostic factors and implications for treatment. Br J Cancer. 1993;68(1):201-207
PubMed   |  Link to Article[[XSLOpenURL/10.1038/bjc.1993.314]]
Weiss SW, Goldblum JR.Liposarcoma.In: Enzinger and Weiss's Soft Tissue Tumors. 5th ed. St Louis, MO: Mosby–Year Book Inc; 2008:477-516.
Mandell DL, Brandwein MS, Woo P, Som PM, Biller HF, Urken ML.Upper aerodigestive tract liposarcoma: report on four cases and literature review. Laryngoscope. 1999;109(8):1245-1252
PubMed   |  Link to Article[[XSLOpenURL/10.1097/00005537-199908000-00012]]
Laurino L, Furlanetto A, Orvieto E, Dei Tos AP.Well-differentiated liposarcoma (atypical lipomatous tumors). Semin Diagn Pathol. 2001;18(4):258-262
Rosai J, Akerman M, Dal Cin P,  et al. Combined morphologic and karyotypic study of 59 atypical lipomatous tumors: evaluation of their relationship and differential diagnosis with other adipose tissue tumors (a report of the CHAMP Study Group). Am J Surg Pathol. 1996;20(10):1182-1189
PubMed   |  Link to Article[[XSLOpenURL/10.1097/00000478-199610000-00002]]
Binh MB, Sastre-Garau X, Guillou L,  et al. MDM2 and CDK4 immunostainings are useful adjuncts in diagnosing well-differentiated and dedifferentiated liposarcoma subtypes: a comparative analysis of 559 soft tissue neoplasms with genetic data. Am J Surg Pathol. 2005;29(10):1340-1347
PubMed   |  Link to Article[[XSLOpenURL/10.1097/01.pas.0000170343.09562.39]]
Aleixo PB, Hartmann AA, Menezes IC, Meurer RT, Oliveira AM.Can MDM2 and CDK4 make the diagnosis of well differentiated/dedifferentiated liposarcoma? an immunohistochemical study on 129 soft tissue tumours. J Clin Pathol. 2009;62(12):1127-1135
PubMed   |  Link to Article[[XSLOpenURL/10.1136/jcp.2009.070201]]
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The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
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