Submitted for Publication: December 21, 2010; final revision received September 29, 2011; accepted October 19, 2011.
Author Contributions: All authors had full access to all the data in the study and take responsibility for the integrity of the data and the accuracy of the data analysis. Study concept and design: Abemayor, Dubinett, Sharma, Wu, and St. John. Acquisition of data: Hu, Lau, L. Wang, G. Wang, Schaue, Zhu, Huang, Dennis, Dubinett, Sharma, and St. John. Analysis and interpretation of data: Hu, Elashoff, Dubinett, McBride, Sharma, and St. John. Drafting of the manuscript: Hu, Lau, G. Wang, Lin, Dennis, Dubinett, Sharma, and St. John. Critical revision of the manuscript for important intellectual content: L. Wang, Schaue, Zhu, Huang, Lin, Abemayor, Elashoff, Dubinett, McBride, Sharma, Wu, and St. John. Statistical analysis: Elashoff. Obtained funding: Wu and St. John. Administrative, technical, and material support: Hu, G. Wang, Schaue, Zhu, Huang, Dennis, McBride, Sharma, and St. John. Study supervision: Hu, Abemayor, Dubinett, Wu, and St. John.
Financial Disclosure: None reported.
Funding/Support: This study was supported by the American Academy of Otolaryngology–American Head and Neck Society Surgeon Scientist Career Development Award (Dr St. John), the Tobacco-Related Disease Research Program of the University of California (Dr St. John), the STOP Cancer Foundation (Dr St. John), the Jonsson Comprehensive Cancer Center, and a National Institute of Dental and Craniofacial Research K23 award (Dr St. John).
Previous Presentation: These data were presented at the American Head and Neck Society 2010 Research Workshop on Biology, Prevention, and Treatment of Head and Neck Cancer; October 29, 2010; Arlington, Virginia.