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Original Article |

Transoral Robotic Surgery Alone for Oropharyngeal Cancer:  An Analysis of Local Control

Gregory S. Weinstein, MD; Harry Quon, MD; H. Jason Newman, MD; J. Ara Chalian, MD; Kelly Malloy, MD; Alexander Lin, MD; Arati Desai, MD; Virginia A. Livolsi, MD; Kathleen T. Montone, MD; K. Roger Cohen, MD; Bert W. O’Malley, MD
Arch Otolaryngol Head Neck Surg. 2012;138(7):628-634. doi:10.1001/archoto.2012.1166.
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Objective  To evaluate local control following transoral robotic surgery (TORS) with the da Vinci Surgical System (Intuitive Surgical Inc) as a single treatment modality for oropharyngeal squamous cell carcinoma (OSCC).

Design  Prospective, single-center, observational study.

Setting  Academic university health system and tertiary referral center.

Patients  Thirty adults with previously untreated OSCC.

Intervention  Transoral robotic surgery with staged neck dissection as indicated.

Main Outcome Measures  Local control and margin status.

Results  Thirty patients were enrolled with previously untreated OSCC and no prior head and neck radiation therapy. Follow-up duration was at least 18 months. At the time of diagnosis, 9 tumors were T1 (30%); 16 were T2 (53%); 4 were T3 (13%); and 1 was T4a (3%). The anatomic sites of these primary tumors were tonsil in 14 (47%), tongue base in 9 (30%), glossotonsillar sulcus in 3 (10%), soft palate in 3 (10%), and oropharyngeal wall in 1 (3%). There was only 1 patient (3%) who had a positive margin after primary resection; further resection achieved a final negative margin. Perineural invasion was noted in 3 tumors (10%). No patient received postoperative adjuvant therapy. At a mean follow-up of 2.7 years (range, 1.5-5.1 years), there was 1 patient with local failure (3%).

Conclusion  As the only modality used for treatment of pathologically low-risk OSCCs, TORS provides high local control and is associated with low surgical morbidity.

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Grahic Jump Location

Figure. Orientation of transoral robotic surgical specimen for pathologic analysis. A, Surgical specimen inked and pinned to cork board. B, Transection of surgical specimen to assess adequacy of deep margin.

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Country-Specific Mortality and Growth Failure in Infancy and Yound Children and Association With Material Stature

Use interactive graphics and maps to view and sort country-specific infant and early dhildhood mortality and growth failure data and their association with maternal

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