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Original Article |

Effect of Obesity and Medical Comorbidities on Outcomes After Adjunct Surgery for Obstructive Sleep Apnea in Cases of Adenotonsillectomy Failure

Dylan K. Chan, MD, PhD; Taha A. Jan, MD; Peter J. Koltai, MD
Arch Otolaryngol Head Neck Surg. 2012;138(10):891-896. doi:10.1001/2013.jamaoto.197.
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Objective  To evaluate the effect of body mass index (BMI, calculated as weight in kilograms divided by height in meters squared) and medical comorbidities on outcomes after lingual tonsillectomy and supraglottoplasty performed for obstructive sleep apnea syndrome (OSAS) caused by lingual tonsillar hypertrophy and occult laryngomalacia.

Design  Retrospective case review series

Setting  Academic tertiary referral center

Patients  Children with persistent OSAS after adenotonsillectomy who underwent surgery to correct obstruction at the level of the lingual tonsils and/or supraglottis identified on sleep endoscopy.

Interventions  All children underwent lingual tonsillectomy, supraglottoplasty, or both.

Main Outcome Measures  Change in polysomnographic parameters, including apnea-hypopnea index (AHI), number of nighttime apneas, and lowest oxygen saturation level.

Results  We analyzed the medical records of 84 children with persistent OSAS after adenotonsillectomy who underwent either lingual tonsillectomy (n = 68), supraglottoplasty (n = 24) or both (n = 8). Compared with children with lingual tonsillar hypertrophy, children with occult laryngomalacia were younger, had lower BMI, and were more likely to have a medical comorbidity. Overall, both operations significantly improved the AHI; however, children with comorbidities had significantly higher postoperative AHIs after supraglottoplasty than those without, and overweight children had significantly higher postoperative AHIs after lingual tonsillectomy than those of normal weight. The BMI z-score and age had direct, though weak, correlations with postoperative AHI among all children undergoing either technique of adjunct airway surgery.

Conclusions  Lingual tonsillar hypertrophy and occult laryngomalacia are 2 important causes of residual OSAS after adenotonsillectomy. However, they tend to affect distinct populations of children, and though appropriate surgical correction can improve AHI, cure rates are significantly worse for overweight children undergoing lingual tonsillectomy and for children with medical comorbidities undergoing supraglottoplasty.

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Grahic Jump Location

Figure 1 . Effect of medical comorbidities on outcomes after lingual tonsillectomy (LT) or supraglottoplasty (SGP). A, In a comparison of apnea-hypopnea index (AHI), we see that after LT, children with medical comorbidities had similar outcomes to those without, but that after SGP, children with medical comorbidities had significantly worse outcomes than those without. *, P < .01. B, Distribution of obstructive sleep apnea (OSA) severity in children with (+) or without (-) medical comorbidities.

Place holder to copy figure label and caption
Grahic Jump Location

Figure 2. Effect of BMI on outcomes after lingual tonsillectomy (LT) or supraglottoplasty (SGP). A, In a comparison of apnea-hypopnea index (AHI), we see that after LT, overweight children had significantly worse outcomes than children of normal weight, but after SGP, the 2 groups did not have significantly different outcomes. *, P < .01. B, Distribution of obstructive sleep apnea (OSA) severity in overweight (+) and nonoverweight (-) children.

Place holder to copy figure label and caption
Grahic Jump Location

Figure 3. Correlation between body mass index (BMI) z-score, age, and postoperative apnea-hypopnea index (AHI). For children undergoing either supraglottoplasty (SPG) or lingual tonsillectomy (LT) for obstructive sleep apnea syndrome after adenotonsillectomy, postoperative AHI had a weak but positive correlation with BMI z-score (A) and age (B). Ascending line in each graph indicates the best fit line; m2 = 0.16 for both.

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