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Original Article |

Laryngeal Reinnervation for Paralytic Dysphonia in Children Younger Than 10 Years

Marshall E. Smith, MD; Nelson Roy, PhD, CCC-SLP; Dan Houtz, MA, CCC-SLP
Arch Otolaryngol Head Neck Surg. 2012;138(12):1161-1166. doi:10.1001/jamaoto.2013.803.
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Objective  To study the effectiveness of ansa–recurrent laryngeal nerve laryngeal reinnervation to improve glottal incompetence causing dysphonia and dysphagia for children with unilateral vocal fold paralysis.

Design  We reviewed a series of consecutive cases treated from January 1, 2006, through December 31, 2011.

Setting  Otolaryngology division of a children's hospital.

Patients  Thirteen children with unilateral vocal fold paralysis.

Main Outcome Measures  Surgical complications, parent surrogate quality-of-life measures, global overall assessment of improvement, and auditory perceptual assessment.

Results  Thirteen children underwent laryngeal reinnervation. Ages ranged from 2.2 to 8.8 years (mean [SD] age, 5.3 [2.6] years). No major complications were identified. Nine children had preoperative and 6- to 12-month postoperative data on voice and swallowing. Mean parental global voice rating (0 indicates no voice; 100%, normal voice) changed from 43% (range, 20%-65%) preoperatively to 79% (range, 50%-100%) postoperatively. Regarding perceptual assessment, the mean GRBAS (Grade, Roughness, Breathiness, Asthenia, Strain) Rating Scale sum score (0 indicates normal voice; 15, profoundly abnormal voice) improved from 6.3 to 2.9. Parental assessment of dysphagia with liquids also improved for all children with preoperative symptoms and worsened for none.

Conclusions  Our early experience suggests that ansa–recurrent laryngeal nerve laryngeal reinnervation is a safe and effective treatment for unilateral vocal fold paralysis with symptomatic dysphonia and dysphagia in young children. The procedure has advantages compared with other treatments. This option should be discussed with parents when the paralysis is identified. The child should be observed for several years in the event that voice and swallowing symptoms from glottal incompetence do not improve.

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Figures

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Figure 1. Mean parent global rating of voice in the 9 patients undergoing laryngeal reinnervation with preoperative and 6- to 12-month postoperative voice and swallowing data available. Whiskers represent standard deviations.

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Figure 2. Individual parent global rating of voice in the 9 patients undergoing laryngeal reinnervation with preoperative and 6- to 12-month postoperative voice and swallowing data available. Ratings ranged from 0 (no voice) to 100% (normal voice).

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Grahic Jump Location

Figure 3. Individual GRBAS (Grade, Roughness, Breathiness, Asthenia, Strain) Rating Scale sum score in the 9 patients undergoing laryngeal reinnervation with preoperative and 6- to 12-month postoperative voice and swallowing data available. Scores ranged from 0 to 3 for each variable, with a highest possible score of 15.

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Grahic Jump Location

Figure 4. Individual parent impairment rating of dysphagia with liquids in the 9 patients undergoing laryngeal reinnervation with preoperative and 6- to 12-month postoperative voice and swallowing data available. Swallowing function was assessed by parent report regarding difficulty swallowing thin liquids, with responses on a 5-point scale where 1 indicates never; 2, almost never; 3, sometimes; 4, almost always; and 5, always.

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