Submitted for Publication: October 19, 2012; final revision received November 21, 2012; accepted December 19, 2012.
Study concept and design: Jowett, Wöllmer, Mlynarek, Wiseman, Franjic, Böttcher, Knecht, Miller.
Acquisition of data: Jowett, Wöllmer, Krötz.
Analysis and interpretation of data: Jowett, Segal, Miller.
Drafting of the manuscript: Jowett, Miller.
Critical revision of the manuscript for important intellectual content: All authors.
Statistical analysis: Jowett, Böttcher.
Obtained funding: Jowett, Wiseman, Knecht, Miller.
Administrative, technical, and material support: Wöllmer, Krötz, Böttcher.
Study supervision: Wöllmer, Mlynarek, Wiseman, Knecht, Miller.
Conflict of Interest Disclosures: Dr Knecht is member of Advisory Boards of Merck Serono, sanofi aventis, Boehringer Ingelheim, and Bayer Healthcare, Leverkusen. Drs Miller and Franjic are cofounders of AttoDyne Inc (manufacturer of the PIRL system). Dr Miller is author of a patent related to the mechanism of PIRL laser ablation. The remaining authors disclosed no conflicts of interest.
Funding/Support: This research was sponsored in part by a Resident Research Grant from the American Academy of Otolaryngology–Head and Neck Surgery Foundation (AAO-HNSF) Centralized Otolaryngology Research Efforts (CORE) grant program, a Canadian Institute of Photonic Innovations (CIPI) Technology Exploitation Network (TEN) grant, a Canadian Institute of Health Research (CIHR) Banting and Best MSc Award, and a Faculty of Medicine Graduate International Travel Fund and McGill Head and Neck Surgery Fund from McGill University.
Additional Contributions: Torsten König, PhD, of InfraTec, GmbH, assisted with the thermography camera operation and data assessment. Wolfgang Kimmig, MD, Department of Dermatology University Medical Centre Hamburg–Eppendorf, provided access to the erbium:YAG laser.