We're unable to sign you in at this time. Please try again in a few minutes.
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......
Comment & Response |

No Difference in Blood Loss During Endoscopic Sinus Surgery With Total Intravenous Anesthesia?

Luca La Colla, MD1; Andrea Albertin, MD2
[+] Author Affiliations
1Department of Anesthesiology, Universitá degli Studi di Parma, Parma, Italy
2Department of Anesthesiology, Ospedale San Giuseppe, IRCCS Multimedica, Milan, Italy
JAMA Otolaryngol Head Neck Surg. 2013;139(10):1077. doi:10.1001/jamaoto.2013.5044.
Text Size: A A A
Published online


To the Editor We read with interest the article published by Chaaban and colleagues.1 While the authors are to be commended for their study, there are a few points that we think should be addressed.

First, anesthetic technique: While both groups received fentanyl at induction, it is not clear which opioid or analgesic patients received during maintenance. Did patients receive an opioid during maintenance of anesthesia? If yes, how much? This question arises because of the surprisingly high concentrations of propofol required during anesthesia. In fact, it is easy to demonstrate by means of a simple computer simulation that 200 µg/kg/min (or 12 mg/kg/h) corresponds to a propofol concentration of almost 5 µg/mL after less than 1 hour of infusion The possible difference in opioid amounts could have had an impact on the amount of propofol or sevoflurane needed to reach the same level of hypotension.


Sign in

Purchase Options

• Buy this article
• Subscribe to the journal
• Rent this article ?

First Page Preview

View Large
First page PDF preview





October 1, 2013
Mohamad R. Chaaban, MD; Fuad M. Baroody, MD; Ori Gottlieb, MD; Robert M. Naclerio, MD
1Department of Surgery, Section of Otolaryngology–Head and Neck Surgery, University of Chicago Medical Center, Chicago, Illinois
2Department of Anesthesia and Critical Care, University of Chicago Medical Center, Chicago, Illinois
JAMA Otolaryngol Head Neck Surg. 2013;139(10):1077-1078. doi:10.1001/jamaoto.2013.5047.
Also Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
Please click the checkbox indicating that you have read the full article in order to submit your answers.
Your answers have been saved for later.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.


Some tools below are only available to our subscribers or users with an online account.

0 Citations

Sign in

Purchase Options

• Buy this article
• Subscribe to the journal
• Rent this article ?

Related Content

Customize your page view by dragging & repositioning the boxes below.

See Also...
Related Collections