Published Online: October 31, 2013. doi:10.1001/jamaoto.2013.5465.
Study concept and design: Aurora, Sindwani, Sanford.
Acquisition of data: Aurora, Chatterjee, Hentzleman, Prasad, Sindwani.
Analysis and interpretation of data: Aurora, Chatterjee, Hentzleman
Drafting of the manuscript: Aurora, Chatterjee, Hentzleman, Sindwani, Sanford.
Critical revision of the manuscript for important intellectual content: Aurora, Chatterjee, Hentzleman, Prasad.
Statistical analysis: Aurora.
Administrative, technical, or material support: Aurora, Chatterjee, Hentzleman, Sindwani, Sanford.
Study supervision: Aurora, Sindwani.
Developed and performed genomic DNA isolation procedures, flow cytometry, ELISpot assays, and cytokine ELISA: Chatterjee.
Performed flow cytometry and cytokine ELISA: Hentzleman.
Performed genomic DNA isolation for next-generation sequencing: Prasad.
Performed endoscopic lavage: Sindwani, Sanford.
Performed ELISpot assays and analysis of sequencing data: Aurora.
Conflict of Interest Disclosures: None reported.
Additional Contributions: Jo Handelsman, PhD, provided advice in the initial stages of this project. We are grateful to the patients for participating in this study. Sherry Koehm, MSc, performed flow cytometry. John Minnerly, MSc, at MOgene assisted with generating amplicons for 454 sequencing.