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Comment & Response |

Obesity and Laryngopharyngeal Reflux as Risk Factors of Lingual Tonsil Hypertrophy in Patients With Sleep-Disordered Breathing: Validity of the Statistical Approach

Tomoyuki Kawada, MD, PhD1
[+] Author Affiliations
1Department of Hygiene and Public Health, Nippon Medical School, Tokyo, Japan
JAMA Otolaryngol Head Neck Surg. 2014;140(3):279-280. doi:10.1001/jamaoto.2013.6453.
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To the Editor I read with interest the study by Sung et al1 for 97 patients with sleep-disordered breathing. They concluded that laryngopharyngeal reflux and body mass index were independent risk factors of lingual tonsil hypertrophy (LTH). I present some statistical concerns about their study.

First, they described that multiple stepwise regression analyses were performed for the risk assessment. But they presented significant and insignificant factors simultaneously in their Table 3. I suppose that they used forced entry method instead of stepwise selection method.


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March 1, 2014
Jeong-Whun Kim, MD, PhD
1Department of Otorhinolaryngology, Seoul National University College of Medicine, Seoul National University Bundang Hospital, Seongnam, Korea
JAMA Otolaryngol Head Neck Surg. 2014;140(3):279-280. doi:10.1001/jamaoto.2013.6468.
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