Completely deidentified data for all cases of SGCA for the years 1988 to 2010 were acquired from the National Cancer Institute’s Surveillance, Epidemiology, and End Results (SEER) database on limited-use terms. Institutional review board review and informed consent were not required because the data were deidentified prior to our interaction with the data. The follow-up cutoff date for the November 2012 submission used in this analysis was December 31, 2010. The flowchart for the cohort selection is shown in Figure 1. Patients whose diagnosis was made at death or autopsy and those with incomplete demographic information were excluded from the analysis. Patients were also excluded if the SGCA was not the patient’s first cancer. Included primary sites as defined by the American Joint Committee on Cancer were identified by the following site codes: Parotid Gland (C079), Submandibular Gland (C080), Sublingual Gland (C081), Overlapping Lesion of Major Salivary Glands (C088), and Major Salivary Gland Not Otherwise Specified (C089). Histology codes were based on the SEER Histology Recode–Broad Groupings: epithelial, not otherwise specified (NOS) (01); squamous cell (02); adenomas and adenocarcinomas (05); mucoepidermoid neoplasms (07); cystic, mucinous, and serous (08); ductal and lobular (09); acinar cell (10); complex epithelial (11); complex mixed and stromal (21). Information for a unique patient identifier, sex, age at diagnosis, year of diagnosis, sequence number, tumor size, tumor extension, lymph node involvement, surgical treatment, radiation use and method, race, Hispanic ethnicity, survival time, cause of death, vital status at last follow-up, histologic subtype, grade, and source of report were extracted for each case. These parameters were determined by the following SEER variables: Patient ID number, Sex, Age at Diagnosis, Year of Diagnosis, Sequence Number-Central, EOD-Tumor Size, CS Tumor Size, EOD-Extension and CS Extension, EOD-Lymph Node Involv and CS Lymph Nodes, RX Summ-Surg Prim Site and RX Summ-Surgery Type, RX Summ-Radiation, Race Recode (W, B, AI, API [white, black, American Indian, Asian or Pacific islander]), Origin Recode NHIA (North American Association of Central Cancer Registries Hispanic/Latino Identification Algorithm) (Hispanic, Non-Hispanic), Survival Months, Cause of Death to SEER Site Recode, Vital Status Recode, Histology Recode-Broad Groupings, Grade, and Type of Reporting Source, respectively.