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Clinical Challenge | Pathology

A Young Man With Enlarging Unilateral Tonsil Mass QUIZ ONLINE FIRST

Casey Hay, MD1; Rafal Kozielski, MD2; Philomena Behar, MD1,3
[+] Author Affiliations
1Department of Otolaryngology, University at Buffalo, Buffalo, New York
2Department of Pathology, University at Buffalo, Buffalo, New York
3Pediatric Ear, Nose, and Throat Associates, Amherst, New York
JAMA Otolaryngol Head Neck Surg. Published online September 08, 2016. doi:10.1001/jamaoto.2016.2472
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A teenager had enlarged tonsils and recurrent tonsillitis, and one tonsil had a smooth, pedunculated, flesh-colored mass; histologic sections revealed a polypoid structure composed of a fibrovascular core covered by stratified squamous epithelium. What is your diagnosis?

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A, Gross specimen demonstrating oval nodule of gray-pink tonsil tissue with partially cryptic mucosa surface and polypoid oval mass. B-D, Histopathologic images. B and C, Hematoxylin-eosin. D, D2-40 antibody.
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