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Clinical Problem Solving: Pathology |

Pathology Quiz Case 1

Chad A. Glazer, BS; Erik H. Waldman, MD; Ali M. Ansari-Lari, MD, PhD; Jennifer N. Broussard, MD; Julie Brahmer, MD; Ralph P. Tufano, MD
Arch Otolaryngol Head Neck Surg. 2006;132(9):1012. doi:10.1001/archotol.132.9.1012-a.
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A 69-year-old man presented with mild ankyloglossia and mild dysarthria, which were caused by a firm, submucosal mass in the anterior portion of his tongue. The mass involved the deep substance of the anterior portion of the tongue and extended into the floor of the mouth. The posterior portion of the tongue and tongue base was soft and mobile. There was no evidence of lymphadenopathy. Five months earlier, the patient had been diagnosed as having a pleural mesothelioma of the epithelioid subtype after he underwent an open biopsy and attempted decortication. He then elected to receive chemotherapy consisting of pemetrexed (Alimta) and cisplatin. He reported a 50 pack-year history of tobacco use and heavy ethanol consumption in the past but stated that he had not smoked cigarettes for 20 years and currently only occasionally ingested alcohol. Importantly, he denied previous asbestos exposure.

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The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
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