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Clinical Note |

Facial Infiltrating Lipomatosis Physical, Radiological, and Histopathological Findings

Ji-Eon Kim, MD; Joshua A. Gottschall, MD; Ronald P. Bachman, MD; Laurie Nemzer, MS; Balaram Puligandla, MD; Galen Schauer, MD
Arch Otolaryngol Head Neck Surg. 2010;136(3):301-303. doi:10.1001/archoto.2010.21.
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Facial infiltrating lipomatosis (FIL) is a rare congenital disorder associated with infiltration of mature lipocytes into adjacent soft tissue. Common findings include hemifacial enlargement, skeletal overgrowth, ipsilateral macroglossia, cutaneous capillary blush, mucosal neuromas, and dental changes. While benign, recurrence is common after surgical treatment. We report a case of this rare disorder and discuss the physical, radiological, and histopathological findings.

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Figure 1.

A 3½-year-old girl with progressive left hemifacial enlargement. Note enlarged left side of the tongue and mucosal neuromas.

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Figure 2.

Axial T1-weighted fast spin-echo magnetic resonance imaging. Note asymmetric enlargement of left hemitongue and fatty infiltration of left cheek (bright).

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Figure 3.

A hematoxylin-eosin stain (original magnification ×100) of a biopsy specimen taken from the superficial aspect of the tongue shows a neuroma causing a pseudopapillomatous appearance. Additional abnormal nerves (arrows) are present below the surface, surrounded by fibrosis. *There is diffuse infiltration by mature adipocytes. ++Sparse skeletal muscle can be seen in the bottom right.

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