0
We're unable to sign you in at this time. Please try again in a few minutes.
Retry
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
Retry
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......
Clinical Note |

Hemangioblastoma of the Cerebellopontine Angle

Matthew L. Bush, MD; Cedric Pritchett, MD; Mark Packer, MD; Abhik Ray-Chaudhury, MD; Abraham Jacob, MD
Arch Otolaryngol Head Neck Surg. 2010;136(7):734-738. doi:10.1001/archoto.2010.98.
Text Size: A A A
Published online

Extract

Tumors of the cerebellopontine angle (CPA) constitute 6% to 10% of all intracranial neoplasms. Most are vestibular schwannomas (VSs) and meningiomas, but as many as 1 in 5 CPA lesions are of other etiologies.1,2 Hemangioblastomas (HMBs), which are highly vascular tumors of the central nervous system, represent up to 12% of infratentorial, intracranial tumors in adults and typically arise in the cerebellum, spinal cord, and brainstem.3 One in 4 HMBs is associated with von Hippel Lindau (VHL) disease.4 A cerebellar HMB is found in 44% to 72% of patients with VHL disease5; however, involvement of the CPA is uncommon. When present within the CPA, HMBs may mimic VSs because the 2 entities have similar magnetic resonance imaging (MRI) characteristics. Cystic changes are seen in 70% to 75% of all HMBs.6,7 We report our experience with a large CPA HMB, which was initially thought to be an atypical cystic VS. Clinical and histologic findings of HMBs are discussed along with the potential for hearing preservation surgery when these lesions occur in the CPA.

Figures in this Article

Sign in

Purchase Options

• Buy this article
• Subscribe to the journal
• Rent this article ?

First Page Preview

View Large
First page PDF preview

Figures

Place holder to copy figure label and caption
Figure 1.

A T1-weighted axial magnetic resonance image with gadolinium at the level of the internal auditory canal showing enhancement of the left cerebellopontine angle solid tumor along its capsule and septations. Note that the tumor involves the medial 4 mm of the canal.

Graphic Jump Location
Place holder to copy figure label and caption
Figure 2.

A T2-weighted axial magnetic resonance image demonstrating intratumoral hyperintensity as well as highlighting the cystic portion of this left cerebellopontine angle tumor.

Graphic Jump Location
Place holder to copy figure label and caption
Figure 3.

A T1-weighted axial magnetic resonance imaging fluid-attenuated inversion-recovery sequence demonstrating the cerebellar brain parenchymal edema and compression of the fourth ventricle.

Graphic Jump Location
Place holder to copy figure label and caption
Figure 4.

Photomicrographs of the neoplasm. A, Low-power view showing a highly vascular neoplasm consisting of capillaries and small vascular channels scattered among neoplastic cells (hematoxylin-eosin, original magnification ×100). B, High-power view demonstrating stromal cells with atypical hyperchromatic nuclei and copious lipid-laden cytoplasm (hematoxylin-eosin, original magnification ×400).

Graphic Jump Location

Tables

References

Correspondence

CME
Also Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
Please click the checkbox indicating that you have read the full article in order to submit your answers.
Your answers have been saved for later.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.

Multimedia

Some tools below are only available to our subscribers or users with an online account.

212 Views
3 Citations
×

Sign in

Purchase Options

• Buy this article
• Subscribe to the journal
• Rent this article ?

Related Content

Customize your page view by dragging & repositioning the boxes below.

Articles Related By Topic
Related Collections
PubMed Articles
Jobs
brightcove.createExperiences();