Carcinoma of the sphenoid sinuses is rare. A careful search of the literature shows only two cases of malignant disease of the sphenoid sinuses, which were recorded by White1 among 125 patients with retrobulbar neuritis. The diagnosis of malignancy was made on biopsy material. Death was due to involvement of the central nervous system in the form of basilar meningitis. The two cases to be reported were diagnosed during life; in both, autopsy showed invasion of the cranial cavity compressing the adjacent nervous structures.
REPORT OF CASES
Case 1.—M. F., a man, aged 43, a furrier, was admitted to the Montefiore Hospital on Nov. 17, 1927. In November, 1926, the patient had complained of difficulty in nasal breathing. He was subject to frequent colds. In May, 1927, following a submucous resection he experienced shooting pain in the nose and the right eye, boring pain in the right frontal region