0
ARTICLE |

ARGYRIA RESULTING FROM INTRANASAL MEDICATION:  A CLINICAL AND EXPERIMENTAL STUDY

BEN L. BRYANT, M.D.
Arch Otolaryngol. 1940;31(1):127-139. doi:10.1001/archotol.1940.00660010128013.
Text Size: A A A
Published online

Despite the warnings that have appeared occasionally in the literature, many otolaryngologists still deny the danger of the production of generalized argyria from the use of silver-containing intranasal medication. This heedless attitude is abetted by the advertisements of certain manufacturers of such medications. One of them states quite consistently in the advertising pages of medical publications that the solution is "non-toxic, definitely bacteriostatic, and above all, it is markedly soothing to inflamed tissues."

The physician who has seen even a single victim of full-blown argyrosis, with its typical generalized pigmentation of the skin, giving the patient a bronzed blue or slate color which has been described aptly as the appearance of a corpse suddenly come to life, must necessarily have been impressed with the importance of preventing such a condition. Prevention is actually the only treatment, for, although Stillians1 and others have shown that by painstaking and multitudinous injections of

Topics

Sign In to Access Full Content

Don't have Access?

Register and get free email Table of Contents alerts, saved searches, PowerPoint downloads, CME quizzes, and more

Subscribe for full-text access to content from 1998 forward and a host of useful features

Activate your current subscription (AMA members and current subscribers)

Purchase Online Access to this article for 24 hours

First Page Preview

View Large
/>
First page PDF preview

Figures

Tables

References

Correspondence

CME
Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.
NOTE:
Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s "Cited By" API will populate this tab (http://www.crossref.org/citedby.html).
Submit a Comment

Multimedia

Some tools below are only available to our subscribers or users with an online account.

Sign In to Access Full Content

Related Content

Customize your page view by dragging & repositioning the boxes below.

Jobs
brightcove.createExperiences();