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Intracranial Complications in Otolaryngology:  Summaries of the Bibliographic Material Available in the Field of Otolaryngology for 1955-1959

JAMES L. BALDWIN, M.D.
AMA Arch Otolaryngol. 1960;71(1):98-109. doi:10.1001/archotol.1960.03770010102011.
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Despite the multiplicity of chemotherapeutic and antibiotic agents available today, and despite the enthusiastic claims by the pharmaceutical companies for each new antimicrobial product, numerous reports of endocranial complications secondary to infections in the nose, paranasal sinuses, and ear continue to appear in the current literature. Many of these complications were not cured by (in fact, some developed while the patient was on adequate doses of) the appropiate antibiotic agent, secured by bacteriological and sensitivity studies. There is a unanimity of opinion that in the presence of an otorhinogenous endocranial complication surgical eradication of the focus of infection must be performed as well as adequate therapy (usually surgical) for the complication to effect a cure. Antibiotics, anticoagulants, sedatives, and other drugs are important in the over-all management of these problems. The masking effect on these serious complications by antibiotics makes diagnosis more difficult and frequently delays treatment. Also, an increasing

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