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May 1966, Vol 83, No. 5 >
ARTICLE | May 1966

Multiple Primary Carcinomas of the Airways

LAURENCE E. WINTER, MD
Arch Otolaryngol. 1966;83(5):468-471. doi:10.1001/archotol.1966.00760020470012.
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MULTIPLE primary carcinomas of the mouth are fairly common, whereas multiple primary carcinomas of the lung are decidedly uncommon. The following case is an example of five primary malignancies involving both the upper and lower airways.

Report of a Case  A 49-year-old white male truck driver was first admitted to the Minneapolis Veterans Administration Hospital on March 15, 1960 with the complaint of a sore in the mouth for the preceding six weeks. The patient had a history of smoking two packs of cigarettes per day for the past 30 years and consuming an average of one quart of whiskey per day. Examination of the mouth revealed an ulcerated 3-cm lesion with raised borders at the left anterior floor of the mouth with extension to the frenulum. A 1-cm superficial ulcer on the right lower lip was also noted. A chest film at this time was within normal limits. Biopsy

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AAM 2010;304:1493-1495.
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BMJ 2010;341:c5893-c1494.
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