0
We're unable to sign you in at this time. Please try again in a few minutes.
Retry
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
Retry
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......
Clinical Note |

Linear IgA Disease Presenting as Desquamative Gingivitis:  A Pattern Poorly Recognized in Medicine

Esther O'Regan, FDSRCS; Anita Bane, MRCPath; Stephen Flint, MB, PhD; Conrad Timon, FRCS; Mary Toner, FRCPath
Arch Otolaryngol Head Neck Surg. 2004;130(4):469-472. doi:10.1001/archotol.130.4.469.
Text Size: A A A
Published online

Linear IgA disease is a subepidermal blistering disorder of unknown cause. Along with dermatologic blistering, other manifestations include oral ulceration and desquamative gingivitis. We present a case of linear IgA disease that manifested simply as oropharyngeal ulceration and desquamative gingivitis, resulting in considerable delay in diagnosis and treatment. This article (1) highlights the difficulties of diagnosing linear IgA disease when the predominant presenting features are mucosal and (2) reviews the current literature regarding linear IgA disease.

Figures in this Article

Sign in

Create a free personal account to sign up for alerts, share articles, and more.

Purchase Options

• Buy this article
• Subscribe to the journal

Figures

Place holder to copy figure label and caption
Figure 1.

Desquamative gingivitis.

Graphic Jump Location
Place holder to copy figure label and caption
Figure 2.

Ulceration of right fauces.

Graphic Jump Location
Place holder to copy figure label and caption
Figure 3.

Buccal mucosa. Subepithelial split containing eosinophils (hematoxylin-eosin, original magnification ×10).

Graphic Jump Location
Place holder to copy figure label and caption
Figure 4.

Buccal mucosa. Direct immunofluorescence illustrating a linear subepithelial band of IgA (original magnification ×10).

Graphic Jump Location
Place holder to copy figure label and caption
Figure 5.

Pharynx. Strips of epithelium with no underlying stroma (hematoxylin-eosin, original magnification ×4).

Graphic Jump Location

Tables

References

Correspondence

CME
Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.
Submit a Comment

Multimedia

Some tools below are only available to our subscribers or users with an online account.

Web of Science® Times Cited: 9

Sign in

Create a free personal account to sign up for alerts, share articles, and more.

Purchase Options

• Buy this article
• Subscribe to the journal

Related Content

Customize your page view by dragging & repositioning the boxes below.

Related Collections
PubMed Articles
Jobs
brightcove.createExperiences();