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Clinical Note |

Parotid Cysts in Children Infected With Human Immunodeficiency Virus:  Report of 4 Cases

José Juan Morales-Aguirre, MD; Jaime Alberto Patiño-Niño, MD; Mónica Mendoza-Azpiri, MD; Claudia Patricia Villalobos-Acosta, MD; Demóstenes Gómez-Barreto, MD; Carlos de la Torre, MD; Miguel Cashat-Cruz, MD, MSc
Arch Otolaryngol Head Neck Surg. 2005;131(4):353-355. doi:10.1001/archotol.131.4.353.
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Cysts of the parotid glands were initially described in patients infected with human immunodeficiency virus (HIV) in 1988, as multiple cystic lesions associated with cervical lymphadenopathy and demonstrated by computed tomography and magnetic resonance imaging.1 Parotid enlargement has been reported in approximately 1% to 10% of the population infected with HIV-1, mainly in adults.25 In the pediatric HIV population, its prevalence is 1% to 10%.2 In a published series of Mexican children infected with HIV, a prevalence of 2.1% was demonstrated.3 However, information on parotid cysts in children with HIV/AIDS is scarce, as there is just 1 case report from 1991.5 Furthermore, in recent years a reduction in the incidence of this abnormality has been observed with the introduction of highly active antiretroviral therapy (HAART) with protease inhibitors. Therefore, no studies have evaluated the course of children infected with HIV who have parotid cysts. We present 4 cases observed in HIV-positive children treated at the Immunodeficiency Clinic of the Hospital Infantil de México Federico Gómez (Mexico City, México) from 1993 to 2003.4

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Figure.

I maging studies of the 4 patients with parotid cysts (A and B, patient 1; C and D, patient 2; E and F, patient 3; and G and H, patient 4). Initial images are on the left and final images on the right. The intervals between basal and final images were 78, 31, 28, and 43 months, respectively.

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