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 Showing 1-20 of 34 Articles
Original Investigation  FREE
Ryan K. Orosco, MD; Harrison W. Lin, MD; Neil Bhattacharyya, MD

Importance  Direct laryngoscopy, once an inpatient procedure, is now commonly performed in the outpatient setting. To ensure that safety follows the adoption of novel techniques and practice patterns, it is important to analyze the complication and revisit rates of these ambulatory surgery practices.

Objective  To determine ...

Original Investigation 
Mark S. Swanson, MD; Rachael L. Hudson, MD; Nipun Bhandari, MPH; Uttam K. Sinha, MD; Dennis R. Maceri, MD; Niels Kokot, MD

Importance  Chyle fistula is an uncommon complication of neck surgery. A variety of management strategies have been described, including diet restriction, parenteral nutrition, use of pressure dressings, and revision surgery. Octreotide has been used with success in patients with neck and thoracic chyle fistulas, but data regarding ...

Original Investigation 
Scott Shadfar, MD; Alexandar Farag, MD; Andrea M. Jarchow, MD; William W. Shockley, MD

Importance  The ideal alloplastic implant for correction of traumatic nasal deformity has not been adequately examined.

Objective  To evaluate the safety profile and postoperative results of expanded polytetrafluoroethylene (ePTFE) implants used in functional nasal surgery (FNS) in the setting of traumatic nasal deformity.

Design, Setting, and ...

Original Investigation 
Joshua Bakhsheshian, MD; Michelle S. Hwang, BS; Michael Friedman, MD

Importance  Spontaneous cerebrospinal fluid (CSF) leaks are a morbid condition associated with operative intervention for treatment. Understanding associations are key to diagnosis, treatment, and possible early detection.

Objective  To determine the clinical association and odds of having obstructive sleep apnea (OSA) and spontaneous CSF leaks.

Data ...

Original Investigation 
Alexander T. Hillel, MD; Laureano Giraldez, MD; Idris Samad, MB, BCh; Jennifer Gross, MD; Adam M. Klein, MD; Michael M. Johns III, MD

Importance  Voice quality-of-life (VQOL) and perceptual voice outcomes are presumed to worsen following posterior cordotomy with medial arytenoidectomy for bilateral vocal fold immobility (BVFI); however, subjective and objective voice outcomes are not well studied in this postsurgical patient population.

Objective  To evaluate VQOL and perceptual voice ...

Original Investigation 
Julia Kristin, MD; Jörg H. Schipper, MD; Muhammad Jalkhi, MD; Thomas Zahnert, MD; Martin Wagenmann, MD

Importance  Nonchordomatous clival lesions are rare and represent a wide range of different benign and malignant pathologies. For an accurate and specific final diagnosis, biopsy procedures and/or resections followed by histologic examination are mandatory.

Objective  To illustrate the challenges in obtaining a final histologic diagnosis in ...

Observation 
Arya W. Namin, BA; Mary S. Czerny, MD; Jastin L. Antisdel, MD

When approaching a patient with cranial nerve 7 (CN7) palsy, a careful workup must be undertaken in order to rule out the many treatable etiologies, including the malignant and infectious. To guide the need for imaging, a careful medical history must elicit if the CN7 weakness had an ...

Original Investigation 
William G. Albergotti, MD; Joshua J. Sturm, AB; Amanda S. Stapleton, MD; Jeffrey P. Simons, MD; Deepak K. Mehta, MD; David H. Chi, MD

Importance  Supraglottoplasty is a common procedure performed without evidence-based postoperative management plans. Patients are routinely admitted to the intensive care unit (ICU) postoperatively, but this may not be necessary in all cases.

Objective  To determine (1) whether routine admission to the ICU after supraglottoplasty is warranted ...

Clinical Challenge 
Emily Tignor, MD; Suimin Qiu, MD; Shraddha Mukerji, MD

A 5-year-old boy with a 1-year history of a mass gradually growing over the helix of his left auricle underwent surgical resection. The lesion was superficially located in the dermis and filled with a soft white material that appeared as purple-blue crystals. What is the diagnosis?

Clinical Challenge 
Kenny F. Lin, MD; Marc A. Cohen, MD; Vikash K. Modi, MD

An MRI of an infant with a 2-month history of an enlarging left preauricular swelling showed a mass with a well-defined capsule arising within the superficial left parotid gland. The mass was largely of fat signal intensity on both T1- and T2-weighted sequences. What is the diagnosis?

Original Investigation 
Kyle J. Chambers, MD; Nikhila Raol, MD; Phillip C. Song, MD; Gregory W. Randolph, MD; Christopher J. Hartnick, MD

Importance  Vocal fold immobility following injury to the recurrent laryngeal nerve (RLN) may lead to substantial morbidity. A reinnervation treatment strategy offers several theoretical benefits over static treatment options. This study evaluates the robustness of reinnervation of the larynx using a split-hypoglossal nerve graft in an animal ...

Original Investigation  FREE
Christopher S. Hollenbeak, PhD; Afif N. Kulaylat, MD; Heath Mackley, MD; Wayne Koch, MD; Eric W. Schaefer, MS; David Goldenberg, MD

Importance  In the United States, nearly 8400 patients die each year from oral cavity and pharynx cancers, most of whom are 65 years and older; however, the costs attributable to these cancers are not well described.

Objective  To identify the primary determinants of cost in patients ...

Original Investigation 
Danielle L. Gainor, MD; Deborah J. Chute, MD; Robert R. Lorenz, MD

Importance  Sodium iodide symporter (NIS) expression in adenoid cystic carcinoma (ACC) has not been fully elucidated in the literature, and it is unclear whether radioactive iodine may be a potential therapeutic modality. To our knowledge, the present study includes the largest ACC tumor sample size to evaluate ...

Clinical Challenge 
Daniel Thomas Ginat, MD, MS; Elizabeth A. Blair, MD

A woman with a history of goiter, hypertension, asthma, obstructive sleep apnea, and skin lesions presented with sore throat, fever, chills, cough, globus sensation, dysphagia, and a change in voice. Laryngoscopy demonstrated diffuse swelling of the supraglottic structures. What is the diagnosis?

Clinical Challenge 
Cong Ran, PhD; Laura J. Tafe, MD; Joseph A. Paydarfar, MD

A young man of Asian heritage presented with a nontender mass in the left parotid region. Physical examination demonstrated a firm, immobile, irregular mass located in the left parotid. FNA demonstrated medium-sized ovoid cells with minimal cytoplasm in crowded groups. What is the diagnosis?

Original Investigation 
Karen J. Cruickshanks, PhD; Sumitrajit Dhar, PhD; Elizabeth Dinces, MD, MS; Robert C. Fifer, PhD; Franklyn Gonzalez II, MS; Gerardo Heiss, MD, PhD; Howard J. Hoffman, MA; David J. Lee, PhD; Marilyn Newhoff, PhD; Laura Tocci, AuD; Peter Torre III, PhD, MS; Ted S. Tweed, MA

Importance  Hearing impairment is common in adults, but few studies have addressed it in the US Hispanic/Latino population.

Objective  To determine the prevalence of hearing impairment among US Hispanic/Latino adults of diverse backgrounds and determine associations with potential risk factors.

Design, Setting, and Participants  The ...

Original Investigation  FREE
Natalie C. Vercillo, MD; Li Xie, ScM; Nidhi Agrawal, MD; Heather C. Nardone, MD

Importance  Tympanostomy tube removal is a commonly performed pediatric procedure. Few studies have evaluated whether removal technique influences the likelihood of the tympanic membrane (TM) to heal.

Objective  To determine whether the technique used for tympanostomy tube removal affects the likelihood of persistent TM perforation healing ...

Clinical Challenge 
Yun-Ting Chao, MD; Wing-Yin Li, MD; Pen-Yuan Chu, MD

A woman in her 50s presented with foreign body sensation in her throat, mild odynophagia, and dyspnea. She had a history of adenoid cystic carcinoma of the right submandibular gland and had undergone wide tumor excision and postoperative radiation therapy. What is the diagnosis?

Original Investigation 
André Ywata de Carvalho, MD, MBA; Thiago C. Chulam, MD, PhD; Luiz P. Kowalski, MD, PhD

Importance  The indication for prophylactic central neck dissection in papillary thyroid cancer (PTC) is controversial.

Objective  To compare long-term results of observation vs prophylactic selective level VI neck dissection for PTC.

Design, Setting, and Participants  We performed a retrospective cohort study of 812 patients with ...

Original Investigation 
Martin M. Bednar, MD, PhD; Nick DeMartinis, MD; Anindita Banerjee, PhD; Stephen Bowditch, MS, CCC-A; Francois Gaudreault, PhD; Laura Zumpano, BS; Frank R. Lin, MD, PhD
Includes: Supplemental Content

Importance  To our knowledge, this is the first study to assess the potential to pharmacologically improve auditory function in adults with age-related sensorineural hearing loss.

Objective  To explore the potential for the α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid potentiator mechanism to affect auditory function in individuals with mild to moderate ...

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