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 Showing 1-20 of 41 Articles
Original Investigation 
Jesse R. Qualliotine, BS; Stephanie F. Coquia, MD; Ulrike M. Hamper, MD, MBA; Carole Fakhry, MD, MPH

Importance  The presence of extranodal extension (ENE) in metastatic papillary thyroid carcinoma (PTC) has emerged as an important prognostic factor, independently associated with tumor persistence after initial resection, decreased likelihood of complete biochemical response, and worse cause-specific survival. Therefore, the ability to determine ENE before surgery is ...

Original Investigation 
Johnathan E. Castaño, MD; Monika E. Freiser, MD, MPH; Hassan H. Ramadan, MD, MSc

Importance  Tonsillectomy is among the most common surgical procedures performed by general and pediatric otolaryngologists. Inpatient surgery is generally recommended for children 36 months and younger owing to concern for a higher incidence of postoperative complications.

Objective  To ascertain the need for a planned inpatient stay ...

Original Investigation 
Ibukun Akinboyewa, BS; Cristina Cabrera-Muffly, MD

Importance  No prior studies have evaluated whether residents who pursue fellowship training achieve higher performance on the Otolaryngology Training Examination (OTE) and whether a specific fellowship will demonstrate a correlation with the corresponding specialty-specific OTE score.

Objectives  To determine whether residents pursuing fellowship training achieve higher ...

Clinical Challenge 
Nathan M. Schularick, MD; Brittany L. Pakalniskis, MD; Rodrigo Bayon, MD

A woman presented with painful swelling along the roof of her mouth and cheek associated with new-onset malocclusion, ipsilateral upper lip numbness, and a submucosal growth on the mesial aspect of the left maxillary alveolus. What is your diagnosis?

Clinical Challenge 
Jason Yuen, MSci, MA, BM, BCh, MRCS; Christopher Burgess, BM, BCh, MA, FRCS(ORL); Ian Bottrill, BM, FRCS(ORL)

A man in his 40s presented with a gradual-onset, left-sided hearing loss with a whistling tinnitus and occasional sharp otalgia; examination showed a smooth mass behind the left tympanic membrane. What is your diagnosis?

Original Investigation 
Courtney A. Hill, MD; Michael Beach, MD, PhD; Mark C. Smith, MD; Eunice Y. Chen, MD

Importance  There are currently no measures of isolated glossopharyngeal taste in healthy children, to our knowledge.

Objective  To define the taste characteristics of an otherwise healthy pediatric population that could serve as a control group for further investigations.

Design, Setting, and Participants  A prospective study ...

Original Investigation 
Justin B. Mahida, MD, MBA; Lindsey Asti, MPH; Emily F. Boss, MD, MPH; Rahul K. Shah, MD; Katherine J. Deans, MD, MHSc; Peter C. Minneci, MD, MHSc; Kris R. Jatana, MD

Importance  Analysis of the American College of Surgeons National Surgical Quality Improvement Program (NSQIP) Pediatric demonstrated that the highest contribution to composite morbidity in otolaryngology is seen in children younger than 2 years undergoing tracheostomy.

Objective  To determine predictive factors for complications following tracheostomy placement in ...

Original Investigation 
Philip Gaudreau, MD, LCDR, MC, USN; M. Taylor Fordham, MD; Tiffany Dong, BA; Xinyang Liu, PhD; Sukryool Kang, PhD; Diego Preciado, MD, PhD; Brian K. Reilly, MD

Importance  The use of 3-dimensional (3D) endoscopy has been described in the pediatric airway and has been shown to improve visualization of complex airway anatomy. Laryngomalacia is one of the most common airway disorders evaluated in pediatric otolaryngology offices. Whether 3D visualization is superior to standard endoscopy ...

Invited Commentary 
Stacey L. Ishman, MD, MPH; Catherine K. Hart, MD

Tracheotomy is commonly performed in the pediatric population, with an estimated 4800 tracheotomy procedures performed on patients under the age of 18 years annually in the United States.1 In particular, infant tracheotomy has previously been identified by Shah et al2 as one of the largest contributors ...

Clinical Challenge 
Scott T. Kramer, MD; Sari Murat, MD; Paul E. Wakely Jr, MD

A young woman had progressive swelling along her right posterior mandible and discomfort with mastication; CT revealed a soft-tissue mass extending into the right retromolar trigone with loss of the intervening fat and soft-tissue planes. What is your diagnosis?

Observation 
A. Sean Alemi, MD; Daniel L. Faden, MD

This case report describes a rare instance of laryngeal involvement in levamisole-induced vasculitis.

Original Investigation 
Rami E. Saade, MD; Diana Bell, MD; Joaquin Garcia, MD; Dianna Roberts, PhD; Randal Weber, MD

Importance  The CRTC1/MAML2 fusion transcript, which arises from the CRTC1/MAML2 translocation, is a molecular marker unique to mucoepidermoid carcinoma (MEC), the most common malignant tumor of the salivary gland. The extent to which the transcript influences disease features and patient survival is unclear.

Objective  To determine ...

Original Investigation 
Yvette E. Smulders, MD; Alice van Zon, MD; Inge Stegeman, PhD; Albert B. Rinia, MD; Gijsbert A. Van Zanten, PhD; Robert J. Stokroos, MD, PhD; Nadia Hendrice, MSc; Rolien H. Free, MD, PhD; Bert Maat, MSc; Johan H. M. Frijns, MD, PhD; Jeroen J. Briaire, PhD; Emmanuel A. M. Mylanus, MD, PhD; Wendy J. Huinck, PhD; Adriana L. Smit, MD; Vedat Topsakal, MD, PhD; Rinze A. Tange, MD, PhD; Wilko Grolman, MD, PhD
Includes: Supplemental Content

Importance  The cost of bilateral cochlear implantation (BCI) is usually not reimbursed by insurance companies because of a lack of well-designed studies reporting the benefits of a second cochlear implant.

Objective  To determine the benefits of simultaneous BCI compared with unilateral cochlear implantation (UCI) in adults ...

Invited Commentary 
Timothy E. Hullar, MD

It is no longer true that cochlear implantation is considered successful if the device simply provides some access between a deaf person and the surrounding auditory world. Our expectations for implants have grown so much that we now aspire for them to create or restore normal or near-normal ...

Review 
Brittany Barber, MD; Jace Dergousoff, MD; Linda Slater, MLIS; Jeffrey Harris, MD, MHA, FRCSC; Daniel O’Connell, MD, MSc, FRCSC; Hamdy El-Hakim, MBChB; Vincent L. Biron, MD, PhD, FRCSC; Nicholas Mitchell, MD, FRCPC; Hadi Seikaly, MD, MAL, FRCSC

Importance  The incidence of depression in patients with head and neck cancer (HNC) is estimated to be as high as 40%. Previous studies have demonstrated an effect of depression on rehabilitation and survival in the posttreatment period.

Objective  To systematically review the relationship between depression and ...

Clinical Challenge 
Allen L. Feng, MD; Heather M. Weinreich, MD, MPH; Edward F. McCarthy, MD

Two years after a woman underwent a retrosigmoid approach for gross resection of a vestibular schwannoma, follow-up imaging revealed residual tumor growth and a region of enhancing tissue involving the left mastoid and jugular foramen. What is your diagnosis?

Clinical Challenge 
Steven Micucci, MD; David S. Bick, MD; Jonathan Sillman, MD

A young woman had otalgia, intermittent rotary vertigo, protrusion of the auricle, and mastoid erythema and tenderness; CT revealed an expansile mass in the mastoid cavity and multiple bilateral cystic lesions and reticular nodular densities. What is your diagnosis?

Viewpoint 
David C. Shonka Jr, MD; David J. Terris, MD

This Viewpoint examines new American Thyroid Association guidelines that recommend a preoperative voice assessment for all patients undergoing thyroid surgery and suggests that the guidelines are deficient in their selective approach to preoperative and postoperative laryngeal examination.

Original Investigation 
Catherine F. Poh, DDS, PhD; Donald W. Anderson, MD; J. Scott Durham, MD; Jiahua Chen, PhD; Kenneth W. Berean, MD; Calum E. MacAulay, PhD; Miriam P. Rosin, PhD

Importance  The prevalence of genetically altered cells in oral cancers has a negative influence on the locoregional recurrence rate and lowers survival. Fluorescence visualization (FV) can identify clinically occult, high-risk oral lesions by allowing health care professionals and surgeons to visualize and map occult disease. This process ...

Original Investigation 
Morgan K. Richards, MD, MPH; John P. Dahl, MD, PhD, MBA; Kenneth Gow, MD; Adam B. Goldin, MD, MPH; John Doski, MD; Melanie Goldfarb, MD; Jed Nuchtern, MD; Monica Langer, MD; Elizabeth A. Beierle, MD; Sanjeev Vasudevan, MD; Douglas S. Hawkins, MD; Sanjay R. Parikh, MD

Importance  Nasopharyngeal carcinoma (NPC) is endemic in some Asian regions but is uncommon in the United States. Little is known about the racial, demographic, and biological characteristics of the disease in pediatric patients.

Objectives  To improve understanding of the differences between pediatric and adult NPC and ...

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