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 Showing 1-20 of 77 Articles
Original Investigation  FREE
Jan S. Lewin, PhD; Leah M. Baumgart, BS; Martha P. Barrow, MPH; Katherine A. Hutcheson, PhD
Includes: Supplemental Content

Importance  Voice prosthesis (VP) device life is a limiting factor of tracheoesophageal (TE) voice restoration that drives patient satisfaction, health care costs, and overall burden. Historic data suggest that TE VPs have an average device life of generally 3 to 6 months, but these data are typically ...

Original Investigation 
Shethal Bearelly, MD; Steven W. Cheung, MD

Importance  Sensory function in the oral cavity and oropharynx is integral to effective deglutition and speech production. The main hurdle to evaluation of tactile consequences of upper aerodigestive tract diseases and treatments is access to a reliable clinical tool. We propose a rapid and reliable procedure to ...

Invited Commentary 
Elliot Abemayor, MD, PhD

Total laryngectomy (TL) as an operation has evolved since it was first performed by Billroth in 1873, and has declined in use as the primary treatment for advanced laryngeal cancer. This decline in use has been arguably associated with a decline in survival rates.1 Less controversial is ...

Clinical Challenge 
Jenna Yousif; Andrew C. Birkeland, MD; Matthew E. Spector, MD

A young man had a significantly elevated calcium level, and imaging revealed a lesion in the location of the right inferior parathyroid gland and lytic bone lesions of the left mandibular ramus, left scapula, and C5 vertebra. What is your diagnosis?

Original Investigation 
Emel Çadallı Tatar, MD; Robbi A. Kupfer, MD; Jonnae Y. Barry, MD; Clint T. Allen, MD; Albert L. Merati, MD

Importance  Management of recurrent respiratory papillomatosis (RRP) in adults has evolved to include office-based laser techniques.

Objective  To determine whether demographic or disease characteristics differ between patients undergoing office-based (office group) vs traditional operating room (OR group) surgical approaches for RRP.

Design, Setting, and Participants  ...

Original Investigation 
McKenzie Tolan, BS; Andrea Serpas, BS; Katherine McElroy, CCC, SLP; Patricia Craun, AuD; Christine Williams, AuD; Brian K. Reilly, MD; Diego Preciado, MD, PhD

Importance  Barriers to early pediatric cochlear implantation in underinsured populations have been previously reported. However, to our knowledge, the effect of this delay on the development of auditory and speech-language objectives has not been evaluated.

Objective  To determine if health care insurance status affects the achievement ...

Original Investigation 
Kapil Wattamwar, BS; Z. Jason Qian, MD; Jenna Otter, MD; Matthew J. Leskowitz, MD; Francesco F. Caruana; Barbara Siedlecki, RN; Jaclyn B. Spitzer, PhD; Anil K. Lalwani, MD
Includes: Supplemental Content

Importance  There is a critical disparity in knowledge regarding the rate and nature of hearing loss in the older old (80 years and older).

Objective  To determine if the rate of age-related hearing loss is constant in the older old.

Design, Setting, and Participants  We ...

Importance  Parental decision making about adenotonsillectomy (AT) for obstructive sleep-disordered breathing (oSDB) is associated with decisional conflict that may be alleviated with improved knowledge about symptoms and treatments.

Objective  To develop a measure of parental knowledge about oSDB and AT.

Design, Setting, and Participants  A ...

Clinical Challenge 
Se-Hyung Kim, MD, PhD

A man had a slow-growing mass on the posterior surface of the left auricle; histopathological examination revealed the tumor to be overall hypocellular and composed of bland spindle cells with no mitotic activity in a slightly basophilic myxoid matrix. What is your diagnosis?

Original Investigation 
Yuan Xu, MD, MSc; Hude Quan, MD, PhD; Peter Faris, PhD; Stephanie Garies, MPH; Mingfu Liu, PhD; Ceris Bird, BSc; Edward Kukec, MBA; Stafford Dean, PhD; Luke Rudmik, MD, MSc

Importance  Reported prevalence rates of chronic rhinosinusitis (CRS) range from 1% to 12% worldwide. To facilitate appropriate health service delivery and resource allocation, it is important to improve the estimated burden of CRS to the health care system.

Objectives  To assess the prevalence and incidence of ...

Original Investigation 
Daniel C. Beachler, PhD, MHS; Eric A. Engels, MD, MPH
Includes: Supplemental Content

Importance  Chronic sinusitis may be involved in the etiology of certain head and neck cancers (HNCs), due to immunodeficiency or inflammation. However, the risk of specific HNCs among people with chronic sinusitis is largely unknown.

Objective  To evaluate the associations of chronic sinusitis with subsequent HNC, ...

Original Investigation 
Morgan K. Richards, MD, MPH; Josephine Czechowicz, MD; Adam B. Goldin, MD, MPH; Kenneth W. Gow, MD; John Doski, MD; Melanie Goldfarb, MD; Jed Nuchtern, MD; Monica Langer, MD; Elizabeth A. Beierle, MD; Sanjeev Vasudevan, MD; Deepti Gupta, MD; Sanjay R. Parikh, MD

Importance  Melanoma in children is rare, accounting for approximately 2% of all pediatric malignant neoplasms. However, for the past 30 years, the incidence of melanoma in those younger than 20 years has been increasing. Location of the primary tumor has been shown to be an important prognostic ...

Invited Commentary 
Elisabeth H. Ference, MD, MPH; Jeffrey D. Suh, MD

Can the inflammation associated with chronic rhinosinusitis (CRS) contribute to the development of head and neck cancer, especially nasal cavity or paranasal sinus cancer? Or is any association between CRS due to reverse causation because nasal and sinus cancer can present initially with sinusitis symptoms?

Clinical Challenge 
Casey Hay, MD; Rafal Kozielski, MD; Philomena Behar, MD

A teenager had enlarged tonsils and recurrent tonsillitis, and one tonsil had a smooth, pedunculated, flesh-colored mass; histologic sections revealed a polypoid structure composed of a fibrovascular core covered by stratified squamous epithelium. What is your diagnosis?

Original Investigation 
Katherine C. Wai, BS; Roberta L. Keller, MD; Leslie A. Lusk, MD; Roberta A. Ballard, MD; Dylan K. Chan, MD, PhD; for the Trial of Late Surfactant (TOLSURF) Study Group

Importance  Tracheotomy is sometimes performed in extremely low gestational age newborns requiring prolonged ventilation. Studies suggest better neurodevelopmental outcomes in preterm newborns undergoing earlier tracheotomy (<120 days); however, guidelines for who should undergo tracheotomy and when to perform tracheotomy are unclear regarding infants receiving long-term positive-pressure support....

Original Investigation 
Yarah M. Haidar, MD; Omid Moshtaghi, BS; Hossein Mahboubi, MD; Yaser Ghavami, MD; Kasra Ziai, MD; Houmehr Hojjat, MD; William B. Armstrong, MD; Hamid R. Djalilian, MD

Importance  In the current health care era, many medical practices are transitioning to a new electronic health record system. Until now, there has been little information published on the association between electronic medical record (EMR) use and otolaryngologist productivity in the ambulatory setting.

Objective  To examine ...

Clinical Challenge 
Cullen M. Taylor, MS; Jennifer Phan, MD; Taha Z. Shipchandler, MD

A man had swelling in the sublingual area and difficulty swallowing; imaging revealed cystic nonenhancing mass centered in the root of the tongue, with elevation of the oral aspect of the tongue and some downward displacement of the floor of mouth. What is your diagnosis?

A woman in her 40s presented to the emergency department with a sclerotic expansion of the right temporal bone and a spiculated periosteal reaction along the outer and inner tables. There was no involvement of any other bones of the calvarium. What is your diagnosis?

Comment & Response 
Swathikan Chidambaram, BSc; En Lin Goh, BSc

To the Editor We thank Schlosser et al1 for their study investigating the link between cytokine levels and loss of olfaction in patients with chronic rhinosinusitis (CRS). By analyzing the composite threshold discrimination identification (TDI) scores and cytokine levels in the mucus, the authors conclude an association ...

Comment & Response 
Rodney J. Schlosser, MD; Jennifer K. Mulligan, PhD; Zachary M. Soler, MD, MSc

In Reply We would like to thank Mr Chidambaram and Mr Goh for their interest in our recent article.1 They commend our study for using validated olfactory metrics, but raise a number of concerns regarding the labile nature of cytokines. Their first point is that the study ...

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