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 Showing 1-20 of 36 Articles
Original Investigation 
Karen J. Cruickshanks, PhD; Sumitrajit Dhar, PhD; Elizabeth Dinces, MD, MS; Robert C. Fifer, PhD; Franklyn Gonzalez II, MS; Gerardo Heiss, MD, PhD; Howard J. Hoffman, MA; David J. Lee, PhD; Marilyn Newhoff, PhD; Laura Tocci, AuD; Peter Torre III, PhD, MS; Ted S. Tweed, MA

Importance  Hearing impairment is common in adults, but few studies have addressed it in the US Hispanic/Latino population.

Objective  To determine the prevalence of hearing impairment among US Hispanic/Latino adults of diverse backgrounds and determine associations with potential risk factors.

Design, Setting, and Participants  The ...

Original Investigation  FREE
Natalie C. Vercillo, MD; Li Xie, ScM; Nidhi Agrawal, MD; Heather C. Nardone, MD

Importance  Tympanostomy tube removal is a commonly performed pediatric procedure. Few studies have evaluated whether removal technique influences the likelihood of the tympanic membrane (TM) to heal.

Objective  To determine whether the technique used for tympanostomy tube removal affects the likelihood of persistent TM perforation healing ...

Clinical Challenge 
Yun-Ting Chao, MD; Wing-Yin Li, MD; Pen-Yuan Chu, MD

A woman in her 50s presented with foreign body sensation in her throat, mild odynophagia, and dyspnea. She had a history of adenoid cystic carcinoma of the right submandibular gland and had undergone wide tumor excision and postoperative radiation therapy. What is the diagnosis?

Original Investigation  FREE
André Ywata de Carvalho, MD, MBA; Thiago C. Chulam, MD, PhD; Luiz P. Kowalski, MD, PhD

Importance  The indication for prophylactic central neck dissection in papillary thyroid cancer (PTC) is controversial.

Objective  To compare long-term results of observation vs prophylactic selective level VI neck dissection for PTC.

Design, Setting, and Participants  We performed a retrospective cohort study of 812 patients with ...

Original Investigation 
Martin M. Bednar, MD, PhD; Nick DeMartinis, MD; Anindita Banerjee, PhD; Stephen Bowditch, MS, CCC-A; Francois Gaudreault, PhD; Laura Zumpano, BS; Frank R. Lin, MD, PhD
Includes: Supplemental Content

Importance  To our knowledge, this is the first study to assess the potential to pharmacologically improve auditory function in adults with age-related sensorineural hearing loss.

Objective  To explore the potential for the α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid potentiator mechanism to affect auditory function in individuals with mild to moderate ...

Case Report/Case Series 
Adolfo M. Bronstein, MD, PhD; Diego Kaski, MBBS, PhD; Nick Cutfield, MBChB, MD; David Buckwell, PhD; Rupan Banga, MRCS; Jaydip Ray, FRCS, PhD; Swarupsinh Chavda, FRCR; Richard Irving, MD, FRCS
Includes: Supplemental Content

Importance  We report a new syndrome, which we are calling head-jolting nystagmus, that expands the differential diagnosis of head movement–induced paroxysmal vertigo.

Observations  Two male patients (65 and 58 years old) described rotational vertigo after violent and brief (1- to 2-second) oscillations of the head ...

Clinical Challenge 
Christopher Clark, MD; Evan Walgama, MD; Matthew W. Ryan, MD

A man in his 30s presented with a worsening sinus infection, nasal drainage, severe headaches, and long-standing visual loss. CT imaging revealed extensive nasal polyposis, bony remodeling consistent with long-standing inflammation, and massive erosion of the bilateral skull base and orbits. What is the diagnosis?

Original Investigation 
Brianna N. Harris, MD, MA; Vincent L. Biron, MD, PhD, FRCSC; Paul Donald, MD, FRCSC; D. Gregory Farwell, MD; Quang C. Luu, MD; Arnaud F. Bewley, MD; Allen M. Chen, MD; Megan E. Daly, MD

Importance  There is no consensus whether primary surgery followed by either adjuvant radiotherapy (RT) or adjuvant chemoradiation (CRT) or definitive CRT should be the standard treatment approach to advanced-stage hypopharyngeal squamous cell carcinoma (HP SCC).

Objectives  To determine survival outcomes for patients with advanced-stage HP SCC ...

Original Investigation  FREE
Alexander L. Luryi, BS; Michelle M. Chen, BA; Saral Mehra, MD, MBA; Sanziana A. Roman, MD; Julie A. Sosa, MD; Benjamin L. Judson, MD

Importance  Most patients with oral cavity squamous cell cancer (OCSCC) are initially seen at an early stage (I and II). Although patient and tumor prognostic features have been analyzed extensively, population-level data examining how variations in treatment factors impact survival are lacking to date.

Objective  To ...

Case Report/Case Series 
Pedrom C. Sioshansi, MD; Gilbert Vezina, MD; Amanda L. Yaun, MD; Marijean M. Miller, MD; Nancy M. Bauman, MD

Importance  Extracranial pituitary ectopia is an uncommon finding characterized by all or a portion of the pituitary gland situated in an aberrant location. Often these lesions come to clinical attention only once they begin to function abnormally or increase in size significantly.

Observations  We describe an ...

Review 
Oleksandr Butskiy, BSc(Hons), MD; Bhavik Mistry, BHSc(Hons); Neil K. Chadha, MBChB(Hons), MPH, BSc(Hons), FRCS

Importance  The most widely used surgical interventions for pediatric unilateral vocal cord paralysis include injection laryngoplasty, thyroplasty, and laryngeal reinnervation. Despite increasing interest in surgical interventions for unilateral vocal cord paralysis in children, the surgical outcomes data in children are scarce.

Objective  To appraise and summarize ...

Clinical Challenge 
Michael Ferra, MD; Peter D. Costantino, MD; Deborah Shatzkes, MD

A woman in her 50s developed severe trismus several months after treatment of a dental abscess. Approximately 10 years after onset of symptoms, she was seen by an oral surgeon who attempted mandibular release via a cervical incision, but the operation was unsuccessful. There was no other significant ...

Viewpoint 
Liana Puscas, MD, MHS; Ramon Esclamado, MD, MS

The recent Viewpoint articles regarding the high number of applications per otolaryngology residency applicant have highlighted the struggle felt by both parties involved in the Match—a desire not just to find a job (the applicant) or an employee (the program), but to make a match that is a ...

Original Investigation  FREE
Michael W. Deutschmann, MD; Kevin J. Sykes, PhD, MPH; John Harbison, MD; Cristina Cabrera-Muffly, MD; Yelizaveta Shnayder, MD

Importance  Posttreatment surveillance (PTS) is a key component in the treatment of patients with head and neck cancer. It is unclear how beneficial this is in improving patients’ survival.

Objective  To determine how compliance with follow-up affects clinical outcomes in patients with head and neck squamous ...

Original Investigation 
Adekunle I. Elegbede, PhD; Lisa A. Rybicki, MS; David J. Adelstein, MD; James A. Kaltenbach, PhD; Robert R. Lorenz, MD; Joseph Scharpf, MD; Brian B. Burkey, MD
Includes: Supplemental Content

Importance  Nonsurgical treatment of advanced supraglottic laryngeal cancer is widely used as part of a larynx preservation protocol. However, recent studies have suggested that nonsurgical treatment may be associated with inferior survival. Furthermore, it is not clear whether preservation of the larynx provides superior voice or swallowing ...

Clinical Challenge 
Yi-Zhi Lin, MD; Yun-Ho Lin, DDS, MS; Shih-Han Hung, MD, MS

A man in his 60s with a history of hyperlipidemia, gout, and sleep apnea was seen an incidental finding of a left torus tubarius, blackish, mucosal lesion. He had no nasal obstruction, nasal bleeding, or feeling of aural fullness. Fibroscopic evaluation revealed a black nevus–like lesion over the ...

Original Investigation 
Tatyana E. Fontenot, MD; Ahmad Deniwar, MD; Parisha Bhatia, MD; Zaid Al-Qurayshi, MD; Gregory W. Randolph, MD; Emad Kandil, MD

Importance  Reoperation for recurrent papillary thyroid cancer (PTC) can be associated with a high rate of complications and failure to provide lasting remission. Percutaneous ethanol injection (PEI) may be an effective nonsurgical management option for locally recurrent PTC.

Objective  This systematic analysis of the current literature ...

Original Investigation 
Osama G. Abdel-Naby Awad, MD; Khalf A. Hamid, MD

Importance  The main objective in the treatment of chronic otitis media is to relieve drainage and to rehabilitate hearing. Various materials can be used to repair the tympanic membrane (TM) through different tympanoplasty techniques.

Objective  To assess the results of endoscopic type I tympanoplasty in pediatric ...

Original Investigation 
Jigar B. Sitapara, MD; Justin B. Mahida, MD, MBA; Timothy P. McEvoy, MD; Charles A. Elmaraghy, MD; Katherine J. Deans, MD, MHSc; Peter C. Minneci, MD, MHSc; Jonathan M. Grischkan, MD, MS

Importance  Congenital nasal pyriform aperture stenosis (CNPAS) is a rare cause of nasal airway obstruction in newborns. The decision to operate is made clinically. Although pyriform aperture width is used for diagnosing CNPAS, it does not fully characterize stenosis of the nasal cavity.

Objective  To determine ...

Special Communication 
Ralph P. Tufano, MD, MBA; Salem I. Noureldine, MD; Peter Angelos, MD, PhD

The worldwide incidence of thyroid cancer is increasing substantially, almost exclusively attributable to small papillary thyroid cancers. Increased use of diagnostic imaging is considered the most likely explanation for this reported rise, but other factors may also be contributing. The increase in health care expenditures related to managing ...

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