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 Showing 1-20 of 66 Articles
Original Investigation  FREE
Humberto C. Sasieta, MD; Vivek N. Iyer, MD, MPH; Diana M. Orbelo, PhD, CCC-SLP ; Cynthia Patton, APRN, CNP, DNP; Rebecca Pittelko, MS, CCC-SLP; Karina Keogh, MD; Kaiser G. Lim, MD, PhD; Dale C. Ekbom, MD

Importance  Refractory chronic cough is a debilitating condition with limited therapeutic options. Laryngeal botulinum toxin type A (BtxA) has been anecdotally reported to benefit patients with chronic cough. We report on our experience with the use of BtxA for the treatment of patients with refractory chronic cough....

Original Investigation 
David J. Sher, MD, MPH; Lucien Nedzi, MD; Saad Khan, MD; Randy Hughes, MD; Baran D. Sumer, MD; Larry L. Myers, MD; John M. Truelson, MD; Matthew Koshy, MD

Importance  There is a growing debate on the relative benefits of adjuvant chemoradiotherapy (CRT) and boost doses of postoperative radiotherapy (B-PORT) in oropharyngeal squamous cell carcinoma (OPSCC) treated with primary surgery, especially for patients with human papillomavirus (HPV)-driven disease.

Objective  To characterize the recent patterns of ...

Original Investigation 
Raquel Novas Cabrera, MD; Carlos T. Chone, MD, PhD; Denise E. Zantut-Wittmann, MD, PhD; Patrcia S. Matos, MD, PhD; Daniel M. Ferreira, MD, PhD; Pablo S. Pereira, MD; Mariana P. Ribeiro, MD; Allan O. Santos, MD, PhD; Celso D. Ramos, MD, PhD; Agrício N. Crespo, MD, PhD; Elba C. Etchebehere, MD, PhD

Importance  Single-photon emission computed tomography/computed tomography (SPECT/CT) and radioguided sentinel lymph node biopsy (rSLNB) are techniques that could potentially benefit surgeons and pathologists in the identification of sentinel lymph node (SLN) metastases in patients with papillary thyroid carcinoma (PTC). Evidence suggests that these novel techniques ...

The use of botulinum toxin injection as a new treatment for chronic (neurogenic) cough is new and novel. In an article by Sasieta and colleagues1 in this issue of JAMA Otolaryngology—Head & Neck Surgery, 22 patients whose chronic coughing had been repeatedly evaluated and treated for ...

Topics: cough; prima trial
Original Investigation 
Arun Sharma, MD, MS; Sapna Patel, MD; Fred M. Baik, MD; Grant Mathison, MD; Brendan H. G. Pierce, MD; Samir S. Khariwala, MD, MS; Bevan Yueh, MD, MPH; Stephen M. Schwartz, MPH, PhD; Eduardo Méndez, MD, MS
Includes: Supplemental Content

Importance  Treatment of oropharyngeal squamous cell carcinoma (OPSCC) presents unique challenges and can be associated with significant morbidity. Transoral robotic surgery (TORS) has emerged as a treatment modality for OPSCC, but data comparing outcomes between patients treated with TORS-based therapy and nonsurgical therapy are limited.

Objective  ...

Original Investigation 
Carissa Wentland, DO; Cheryl Hersh, MA, CCC-SLP; Sarah Sally, MS, CCC-SLP; M. Shannon Fracchia, MD; Steven Hardy, MD; Bob Liu, PhD; Jordan A. Garcia, BS; Christopher J. Hartnick, MD

Importance  There is no consensus as to the timing of videofluoroscopic swallow studies (VFSSs) in determining resolving aspiration after laryngeal cleft repair. There is a growing literature on the effect of radiation exposure in children.

Objective  To modify a previously published best-practice algorithm based on a ...

Original Investigation 
Nicole T. Jiam, BA; Patpong Jiradejvong, MS; Monica S. Pearl, MD; Charles J. Limb, MD
Includes: Supplemental Content

Importance  The round window insertion (RWI) and cochleostomy approaches are the 2 most common surgical techniques used in cochlear implantation (CI). However, there is no consensus on which approach is ideal for electrode array insertion, in part because visualization of intracochlear electrode position is challenging, so postoperative ...

Clinical Challenge 
Michelle M. Chen, MD; Caroline Jeffery, MD; Edward J. Damrose, MD

A woman had a cervical tracheal mass on magnetic resonance imaging for cervical spine pain; flexible fiber-optic nasolaryngoscopy demonstrated a smooth hypervascular mass arising from the posterior membranous trachea. What is your diagnosis?

Original Investigation 
Jason R. Bell, MD; Holly Ruch-Ross, ScD; Andrew J. Hotaling, MD
Includes: Supplemental Content

Importance  This study represents up-to-date information on the current status of and future projections for the pediatric otolaryngology workforce.

Objective  To provide an update on the practice patterns of and projections for the US pediatric otolaryngology workforce.

Design, Setting, and Participants  An online survey was ...

Original Investigation 
Eleftherios Savvas, MD; Steffen Hillmann, MD; Daniel Weiss, MD; Mario Koopmann, MD; Claudia Rudack, MD, PhD; Jürgen Alberty, MD, PhD

Importance  Electrophysiologic facial nerve monitoring is becoming an established intraoperative aid to assist the surgeon in facial nerve trunk or branch location and dissection. Limited studies have addressed the postoperative outcomes of parotid surgery with and without monitoring.

Objective  To examine the influence of intraoperative facial ...

Original Investigation 
Christina L. Runge, PhD; Amit Indap, PhD; Yifan Zhou, PhD; Jack W. Kent Jr, PhD; Ericka King, MD; Christy B. Erbe, BS; Regina Cole, BS; Jack Littrell, MS; Kate Merath, PhD; Roland James, MS; Franz Rüschendorf, PhD; Joseph E. Kerschner, MD; Gabor Marth, PhD; Norbert Hübner, PhD; Harald H. H. Göring, PhD; David R. Friedland, MD, PhD; Wai-Meng Kwok, PhD; Michael Olivier, PhD

Importance  Sensorineural hearing loss (SNHL) is commonly caused by conditions that affect cochlear structures or the auditory nerve, and the genes identified as causing SNHL to date only explain a fraction of the overall genetic risk for this debilitating disorder. It is likely that other genes and ...

Michael Armstrong Jr, MD; Gael B. Strack, Esq

Importance  Strangulation accounts for 10% of violent deaths in the United States and 15% to 20% of deaths associated with domestic violence. However, strangulation deaths represent only a small fraction of nonfatal strangulation assaults, which occur with daily frequency in medium to large US cities. Careful evaluation ...

Original Investigation 
Sapideh Gilani, MD; Melissa A. Pynnonen, MD; Jennifer J. Shin, MD, SM
Includes: Supplemental Content

Importance  Antireflux medication has been endorsed as a useful adjunctive therapy for chronic rhinosinusitis, but its use remains controversial.

Objectives  To determine whether chronic rhinosinusitis is associated with administration of proton pump inhibitors, histamine2-receptor antagonists, antacids, or prokinetic agents; whether practice patterns vary according ...

Original Investigation 
Amal Isaiah, MD, DPhil; Kelly Moyer, MD; Kevin D. Pereira, MD, MS

Importance  The indications for neonatal tracheostomy may have changed with current noninvasive respiratory therapies compared with previous decades.

Objectives  To study the current trends in neonatal tracheostomy and identify the primary indication for the procedure and risk factors for failed extubation.

Design, Setting, and Participants  ...

Invited Commentary 
Jonathan M. Bock, MD; David M. Poetker, MD

No disease has been implicated more frequently as a comorbid cause of upper airway diseases than gastroesophageal reflux disease. Supraesophageal reflux of stomach acid has been suggested to lead to a large number of otolaryngologic conditions, including such disparate morbidities as dysphonia, laryngospasm, vocal cord dysfunction, globus sensation, ...

Clinical Challenge 
Kristy Truong, MD; Robert Robinson, MD; Henry Hoffman, MD

A woman presented with right submandibular swelling and pain, associated with eating, and inability to express saliva on examination; a sialogram showed a high-grade stricture into the right submandibular duct orifice. What is your diagnosis?

Original Investigation 
Victoria S. Lee, MD; Kelly N. Evans, MD; Francisco A. Perez, MD, PhD; Assaf P. Oron, PhD; Jonathan A. Perkins, DO
Includes: Supplemental Content

Importance  Airway management in infants with Robin sequence is challenging. Objective upper airway measures associated with severe airway compromise requiring tracheotomy are needed to guide decision making.

Objectives  To define objective upper airway measures in infants with Robin sequence from craniofacial computed tomography (CT) and to ...

Original Investigation 
John M. Carter, MD; Jeffrey C. Rastatter, MD; Bharat Bhushan, PhD; John Maddalozzo, MD

Importance  Limited information exists about the short-term morbidity of parotidectomy in children. This information is important when counseling parents and planning treatment for children with parotid masses.

Objective  To examine 30-day perioperative outcomes after parotidectomy in the pediatric population.

Design, Setting, and Participants  A prospective ...

Original Investigation 
Ansley M. Roche, MD; Stacey A. Fedewa, MPH; Amy Y. Chen, MD, MPH
Includes: Supplemental Content

Importance  Medullary thyroid cancer (MTC) is a relatively rare neoplasm of the thyroid but accounts for 14% of thyroid cancer–related deaths. Female sex, young age, and stage at presentation have been found to predict survival and treatment. However, patterns of survival and treatment by socioeconomic status and ...

Clinical Challenge 
Derek Kai Kong, MS; Christopher A. Schutt, MD; Elias Michaelides, MD

A man had recurrent episodes of unilateral high-pitched “clicking” in his right ear followed by vertigo that lasted 3 to 4 seconds but no hearing loss, aural fullness, autophony, or headache. What is your diagnosis?

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