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 Showing 1-20 of 65 Articles
Original Investigation  FREE
Steven Arild Wuyts Andersen, MD; Lars Konge, MD, PhD; Per Cayé-Thomasen, MD, DMSc; Mads Sølvsten Sørensen, MD, DMSc
Includes: Supplemental Content

Importance  The ultimate goal of surgical training is consolidated skills with a consistently high performance. However, surgical skills are heterogeneously retained and depend on a variety of factors, including the task, cognitive demands, and organization of practice. Virtual reality (VR) simulation is increasingly being used in surgical ...

Original Investigation 
Andrew M. Hinson, MD; Samuel F. Hohmann, PhD; Brendan C. Stack Jr, MD

Importance  To improve outcomes after parathyroidectomy, several organizations advocate for selective referral of patients to high-volume academic medical centers with dedicated endocrine surgery programs. The major factors that influence whether patients travel away from their local community and support system for perceived better care remain elusive.

Objective...

Original Investigation 
Robert Chun, MD; Noel Jabbour, MD; Karthik Balakrishnan, MD, MPH; Nancy Bauman, MD; David H. Darrow, MD; Ravindhra Elluru, MD; J. Fredrik Grimmer, MD; Jonathan Perkins, DO; Gresham Richter, MD; Jennifer Shin, MD

Importance  The field of vascular anomalies presents diverse challenges in diagnosis and management. Although many lesions involve the head and neck, training in vascular anomalies is not universally included in otolaryngology residencies and pediatric otolaryngology (POTO) fellowships.

Objective  To explore the education in, exposure to, and ...

Clinical Challenge 
Jose Ting; Diana M. Bell, MD; Carol M. Lewis, MD, MPH

A man had singular, umbilicated, ulcerated papular lesion of the temple with overlying crusts and surrounding erythema and induration; CT with contrast of the soft tissue revealed an abnormal mass in the site of the lesion. What is your diagnosis?

Clinical Challenge 
Michael Canfarotta, BS; Poornima Hegde, MD; Kourosh Parham, MD, PhD

A man had an elevated serum ionized calcium level; joint, back, and abdominal pain; constipation; fatigue; and depression; he underwent a parathyroid exploration and excision of a soft, ovoid tissue, believed to be a slightly enlarged left inferior parathyroid gland. What is your diagnosis?

Comment & Response 
Richard T. Kloos, MD; Neil M. Barth, MD

To the Editor Noureldine and colleagues1 found that molecular testing with the Afirma gene expression classifier (GEC) did not have a significant effect on the surgical decision-making process for patients with thyroid nodules who presented for surgical consultation. However, this study1 evaluates the test’s performance using ...

Comment & Response 
Salem I. Noureldine, MD; Martha A. Zeiger, MD; Ralph P. Tufano, MD, MBA

In Reply Drs Kloos and Barth,1 employees and equity owners of Veracyte raise questions about the design and findings of our study examining the effect of Veracyte’s Afirma gene expression classifier (GEC) on the practice of 10 thyroid surgeons at an academic institution.2

Original Investigation 
Jon Mallen-St. Clair, MD, PhD; Armin Arshi, BS; Elliot Abemayor, MD, PhD; Maie St. John, MD, PhD

Importance  Synovial cell sarcoma of the head and neck (SCSHN) is a rare tumor associated with significant morbidity and mortality. The literature regarding these tumors is limited to case series and case reports. We used data from the population-based US Surveillance, Epidemiology, and End Results (SEER) cancer ...

Original Investigation 
Zaid Al-Qurayshi, MD, MPH; Gregory W. Randolph, MD; Mohammed Alshehri, MD; Emad Kandil, MD

Importance  Intraoperative nerve monitoring (IONM) is increasingly performed during thyroid surgery.

Objective  To examine the use of IONM and its association with patient demographic characteristics and surgeon volume.

Design, Setting, and Participants  A cross-sectional analysis used the State Inpatient Databases from January 1, 2010, to ...

Original Investigation 
Jacqueline E. Weinstein, MD; Ashwin Ananth, MD, MBA; Jacob P. Brunner, MD; Ryan E. Nelson, MD; Marjorie E. Bateman, BS; John M. Carter, MD; Joseph F. Buell, MD, MBA; Paul L. Friedlander, MD
Includes: Supplemental Content

Importance  Human papillomavirus (HPV) is a preventable disease that plays a causative role in a significant proportion of malignant neoplasms of the head and neck. Inner-city populations are at risk for HPV-related oropharyngeal cancer, are least likely to receive HPV vaccination, and report a lack of information ...

Clinical Challenge 
Rachel A. Kominsky, BS; Jason Bell, MD; Monica O. Patadia, MD

A young black man had progressive bilateral parotid swelling; radiologically, there were no masses or sialoliths, and his only associated symptoms were fevers and fatigue. What is your diagnosis?

Clinical Challenge 
Joshua D. Horton, BS; Eric W. Cerrati, MD; Cheng Z. Liu, MD, PhD

A man had a left parotid gland lesion, with no associated pain, facial numbness, or weakness; computed tomography revealed a well-circumscribed ovoid lesion in the anterior aspect of the superficial lobe of the left parotid gland. What is your diagnosis?

Clinical Challenge 
Marco Mandalà, MD, PhD; Enrico Muzzi, MD; Franco Trabalzini, MD

A woman who had undergone an emergency craniotomy for brain decompression had purulent discharge from her right ear; imaging detected middle ear, mastoid, and infralabyrinthine involvement and meningitis and a large cerebellar lesion. What is your diagnosis?

Comment & Response 
Maria Pia Villa, MD; Ottavio Vitelli, MD, PhD; Melania Evangelisti, MD, PhD

To the Editor We read with great interest the article titled “The Role of Sleep Studies in Children Who Snore” by Ishman.1 In this article the author reaffirmed the importance of performing polysomnography in children with suspected sleep disordered breathing (SDB) before and especially after treatment because ...

Comment & Response 
Stacey Ishman, MD, MPH

In Reply I thank Dr Villa et al1 for their comments regarding our article2 and appreciate their bringing my attention to their work to develop and validate the sleep clinical record.35 I agree with these authors that, while sleep studies are considered to ...

Original Investigation 
Kevin Y. Zhan, MD; Evan M. Graboyes, MD; Shaun A. Nguyen, MD, MA; Terry A. Day, MD

Importance  Thirty-day unplanned readmissions are increasingly used as a measure of quality care.

Objective  To describe the incidence of and risk factors for 30-day unplanned readmissions for patients undergoing treatment for cancer of the parotid gland.

Design, Setting, and Participants  A retrospective cohort study was ...

Original Investigation 
Andrew C. Birkeland, MD; Megan Yanik, BS; Brittny N. Tillman, MD; Megan V. Scott, BS; Susan K. Foltin, BS; Jacqueline E. Mann, BS; Nicole L. Michmerhuizen, BS; Megan L. Ludwig, BS; Morgan M. Sandelski, BS; Christine M. Komarck, BS; Thomas E. Carey, PhD; Mark E. P. Prince, MD; Carol R. Bradford, MD; Jonathan B. McHugh, MD; Matthew E. Spector, MD; J. Chad Brenner, PhD
Includes: Supplemental Content

Importance  ERBB2 (formerly HER2) is an important drug target in breast cancer, where anti-ERBB2 therapy has been shown to lead to improvements in disease recurrence and overall survival. ERBB2 status in head and neck squamous cell carcinoma (HNSCC) has not been well studied. Identification of ERBB2...

Original Investigation 
S. Andrew Skillington, BA; Dorina Kallogjeri, MD, MPH; James S. Lewis Jr, MD; Jay F. Piccirillo, MD

Importance  Comorbidity affects the prognosis of patients with cancer through the direct effects of the comorbid illness and by influencing the patients’ ability to tolerate treatment and mount a host response. However, the prognostic importance of comorbidity in oropharyngeal squamous cell carcinoma is not well characterized in ...

Clinical Challenge 
Daniel D. Tran, MD; Lauren K. Reckley, MD; Scott B. Roofe, MD

A woman had a progressively enlarging lump on her tongue; the size caused intermittent gagging and a foreign-body sensation in her throat; examination revealed a pedunculated mass of the posterior dorsal tongue just lateral to the circumvallate papillae. What is your diagnosis?

Clinical Challenge 
Joseph Spellman, MD; James Valentine, MD; Anil Shah, MD

A woman had severe frontal and periorbital headaches and multiple prominent soft, tender nodules at the forehead and right orbit with right proptosis; a computed tomographic scan showed a soft-tissue mass with involvement of multiple craniofacial bones. What is your diagnosis?

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