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 Showing 1-20 of 26 Articles
Original Investigation 
Soroush Zaghi, MD; Jon-Erik C. Holty, MD, MS; Victor Certal, MD; Jose Abdullatif, MD; Christian Guilleminault, DM, MD, DBiol; Nelson B. Powell, MD, DDS; Robert W. Riley, MD, MS, DDS; Macario Camacho, MD
Includes: Supplemental Content

Importance  Maxillomandibular advancement (MMA) is an invasive yet effective surgical option for obstructive sleep apnea (OSA) that achieves enlargement of the upper airway by physically expanding the facial skeletal framework.

Objective  To identify criteria associated with surgical outcomes of MMA using aggregated individual patient data from ...

Original Investigation 
Salem I. Noureldine, MD; Matthew T. Olson, MD; Nishant Agrawal, MD; Jason D. Prescott, MD, PhD; Martha A. Zeiger, MD; Ralph P. Tufano, MD, MBA

Importance  Commercial molecular testing, such as the gene expression classifier (GEC), is now being used in the work up of cytologically indeterminate thyroid nodules. While this test may be helpful in ruling out malignancy in a thyroid nodule, its effect on surgical decision making has yet to ...

Original Investigation 
William J. Moss, MD; Harrison W. Lin, MD; Roberto A. Cueva, MD
Includes: Supplemental Content

Importance  Surgical repair of congenital aural atresia and hypoplasia (CAAH) is technically challenging. Long-term surgical and audiologic outcomes of atresiaplasty are incompletely understood.

Objectives  To review the surgical outcomes for CAAH and analyze the hearing results.

Design, Setting, and Participants  A retrospective medical record review ...

Peter M. Vila, MD, MSPH; John S. Schneider, MD, MA; Jay F. Piccirillo, MD; Judith E. C. Lieu, MD, MSPH

As health care reimbursements based on pay-for-performance models become more common, there is an unprecedented demand for ways to measure health care quality and demonstrate value. Performance measures, a type of quality measure, are unique tools in a health care delivery system that allow objective monitoring of adherence ...

Clinical Challenge 
Rachel Barry, MD; Abhita Reddy; Anita Jeyakumar, MD, MS

A young girl with a 10-day history of otitis media and fevers was found to have a bulging, hyperemic left tympanic membrane and fullness of the postauricular, upper cervical region. What is your diagnosis?

Original Investigation 
Victoria A. Costa, BS; Rachel Haimowitz, BS; Yao I. Cheng, MS; Jichuan Wang, PhD; Robert A. Silverman, MD; Nancy M. Bauman, MD

Importance  Involuted infantile facial hemangiomas (IHs) may adversely affect the social skills of children.

Objective  To assess the social impact of involuted facial IHs, with or without prior treatment, in preteen children.

Design, Setting, and Participants  An observational, cross-sectional study of social anxiety and skills ...

Original Investigation 
Pamela Mukhatiyar, MD; Kiran Nandalike, MD; Hillel W. Cohen, DrPH, MPH; Sanghun Sin, MS; Mona Gangar, MD; John P. Bent, MD; Raanan Arens, MD

Importance  Limited information exists regarding clinical outcomes of children undergoing extracapsular tonsillectomy and adenoidectomy (ETA) or intracapsular tonsillectomy and adenoidectomy (ITA) for treatment of obstructive sleep apnea syndrome (OSAS).

Objectives  To quantify polysomnography (PSG) and clinical outcomes of ETA and ITA in children with OSAS and ...

Mehdi Taghipour, MD; Sara Sheikhbahaei, MD, MPH; Wael Marashdeh, MD; Lilja Solnes, MD; Anna Kiess, MD, PhD; Rathan M. Subramaniam, MD, PhD, MPH
Includes: Supplemental Content

18F-fludeoxyglucose–positron emission tomography/computed tomography (FDG-PET/CT) has been performed widely in diagnosis and management of patients with oropharyngeal squamous cell carcinoma (OPSCC). This review summarizes the literature on this tool in the management of these patients. The use of FDG-PET/CT helps in accurate staging of primary tumor, nodal ...

Clinical Challenge 
Rebecca Harvey, MD; Jonathan McHugh, MD; Jesse Ryan, MD

A CT scan of the neck of a woman who had slowly enlarging neck mass showed a cystic neck mass in the left floor of mouth; a core biopsy specimen showed a well-differentiated papillary neoplasm with hyalinized fibrovascular cores and degenerative changes. What is your diagnosis?

Original Investigation 
David Kam, BS; Andrew Salib, BA; George Gorgy, BA; Tapan D. Patel, MD; Eric T. Carniol, MD, MBA; Jean Anderson Eloy, MD; Soly Baredes, MD; Richard Chan Woo Park, MD

Importance  Suicide rates among patients with cancer in the US are significantly higher than those of the general population. To our knowledge, large cohort studies examining suicide rates among patients with head and neck cancer have not been performed.

Objective  To identify incidence rate, trends, and ...

Original Investigation 
Zaid Al-Qurayshi, MD, MPH; Russell Robins, PhD; Adam Hauch, MD, MBA; Gregory W. Randolph, MD; Emad Kandil, MD
Includes: Supplemental Content

Importance  Incidence of thyroidectomies is continuing to increase. Identifying factors associated with favorable outcomes can lead to cost savings.

Objective  To assess the association of surgeon volume with clinical outcomes and costs of thyroidectomy.

Design, Setting, and Participants  Cross-sectional analysis performed in October of 2014 ...

Original Investigation 
Christen J. Lennon, MD; Alexander Gelbard, MD; Carmin Bartow, MS; C. Gaelyn Garrett, MD; James L. Netterville, MD; Christopher T. Wootten, MD
Includes: Supplemental Content

Importance  Patients who undergo open airway reconstruction procedures are likely to experience some degree of postoperative dysphagia symptoms and delayed return to oral intake.

Objective  To review the duration of postoperative dysphagia symptoms and outcomes in a group of adult patients.

Design, Setting, and Participants  ...

Aria Jafari, MD; Joseph Acevedo, BS; Marc Lebovits, MD

This case report describes a patient with refractory headache with incidental bilateral nasopharyngeal cysts later confirmed to be mucopyoceles.

Original Investigation 
Dhruv Kumar, PhD; Christopher Kandl, MD; Chase D’Arcy Hamilton, BS; Yelizaveta Shnayder, MD; Terance Ted Tsue, MD; Kiran Kakarala, MD; Levi Ledgerwood, MD; Xiuzhi Susan Sun, PhD; Hongzhou (John) Huang, PhD; Douglas Girod, MD; Sufi Mary Thomas, PhD

Importance  Ficlatuzumab can be used to treat head and neck squamous cell carcinoma (HNSCC) by inhibiting c-Met receptor-mediated cell proliferation, migration, and invasion.

Objective  To understand the effect of ficlatuzumab on HNSCC proliferation, migration, and invasion.

Design, Setting, and Participants  The effects of ficlatuzumab on ...

Original Investigation 
Yuval Nachalon, MD; Sagit Stern-Shavit, MD; Gideon Bachar, MD; Jacob Shvero, MD; Dror Limon, MD; Aron Popovtzer, MD

Importance  Anaplastic thyroid carcinoma is an undifferentiated aggressive tumor with a high rate of regional and distant spread and a grave prognosis (median survival, 3 months) with no standardized treatment.

Objective  To review the effect of an active treatment policy on the outcome of anaplastic thyroid ...

Original Investigation 
JeeHong Kim, BS; Seungwon Kim, MD; William G. Albergotti, MD; Phillip A. Choi, BS; Daniel James Kaplan, BA; Shira Abberbock, MS; Jonas T. Johnson, MD; Neil Gildener-Leapman, MD

Importance  Salvage surgery for recurrent head and neck squamous cell carcinoma (HNSCC) carries substantial risks of morbidity and mortality. Risk factors for death within 1 year should be better defined.

Objectives  To report preoperative oncologic prognostic factors predictive of short-term (<1 year) survival after salvage surgery ...

Original Investigation 
Laura M. Enomoto, MD; Eric W. Schaefer, MS; David Goldenberg, MD; Heath Mackley, MD; Wayne M. Koch, MD; Christopher S. Hollenbeak, PhD

Importance  Hospice care has been suggested as a way to preserve dignity and to lower costs at the end of life, which may be particularly important for patients with head and neck cancer because this disease is associated with considerable morbidity and a high mortality risk.


Original Investigation 
John R. de Almeida, MD, MSc; Ryan Li, MD; J. Scott Magnuson, MD; Richard V. Smith, MD; Eric Moore, MD; Georges Lawson, MD; Marc Remacle, MD; Ian Ganly, MD; Dennis H. Kraus, MD; Marita S. Teng, MD; Brett A. Miles, MD; Hilliary White, MD; Umamaheswar Duvvuri, MD, PhD; Robert L. Ferris, MD, PhD; Vikas Mehta, MD; Krista Kiyosaki, MD; Edward J. Damrose, MD; Steven J. Wang, MD; Michael E. Kupferman, MD; Yoon Woo Koh, MD; Eric M. Genden, MD; F. Christopher Holsinger, MD
Includes: Supplemental Content

Importance  Large patient cohorts are necessary to validate the efficacy of transoral robotic surgery (TORS) in the management of head and neck cancer.

Objectives  To review oncologic outcomes of TORS from a large multi-institutional collaboration and to identify predictors of disease recurrence and disease-specific mortality.

Design, ...

Correction  FREE

In the Original Investigation titled “Factors Associated With Hospital Length of Stay Following Fibular Free-Tissue Reconstruction of Head and Neck Defects: Assessment Using the American College of Surgeons National Surgical Quality Improvement Program (ACS NSQIP) Criteria,”1 published online April 23, 2015, there was an omission in the ...

Original Investigation 
Marcus J. Magister, MD; Irina Chaikhoutdinov, MD; Eric Schaefer, MS; Nicole Williams, MD; Brian Saunders, MD; David Goldenberg, MD

Importance  The ability to accurately stratify patients with thyroid nodules (TNs) preoperatively is imperative because most TNs are benign. The reliability of fine-needle aspiration biopsy (FNAB) in large TNs has been questioned in recent literature.

Objective  To determine whether TN size affects the reliability of FNAB ...

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